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Noel; Relationship between endometriotic foci and nerves in rectovaginal endometriotic nodules, Human ReproductionVolume 15, Issue 8, 1 AugustPages —, ahaf The histological relationships between fibrotic tissue, endometriotic foci and nerves in the rectovaginal septum endometriotic or adenomyotic nodule were studied.

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This is considered to be one of the most severe forms of deep endometriosis. Masson’s trichrome staining for fibrosis detection and immunohistochemistry with the 70 monoclonal antibody for nerve detection were performed in 28 rectovaginal endometriotic nodules from patients presenting with severe dysmenorrhoea and deep dyspareunia 23 patients with no other endometriotic location or potential cause of pain at laparoscopy and ultrasonography; five patients with multiple anat endometriotic localizations and ansf potential causes of pain at laparoscopy.

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For each symptom, the mean number of nerves and endometriotic lesions per high-power field and the mean largest diameter of the lesions were not statistically different in groups 1 and 2. The mean percentages of nerves located within the fibrosis of the nodule and within endometriotic lesions were significantly higher in group 1 than in group 2.

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Among nerves located within endometriotic lesions, there was a anaff higher proportion showing intraneurial and perineurial invasion by endometriosis in group 1 than in group 2. In rectovaginal endometriotic nodules, there was a close histological relationship between nerves and endometriotic foci, and between nerves and the fibrotic component of the nodule.

We postulate that such topographical relationships could at least partially explain the strong association between this lesion and pain. Oxford University Press is a department of the University of Oxford.

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It furthers the University’s objective of excellence in wnaf, scholarship, and education by publishing worldwide. Sign In or Create an Account. Close mobile search navigation Article navigation. Relationship between endometriotic foci and nerves in rectovaginal endometriotic nodules V. Abstract The histological relationships between fibrotic tissue, endometriotic foci and nerves in the rectovaginal septum endometriotic or adenomyotic nodule were studied.

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Email alerts New issue alert. Receive exclusive offers and updates from Oxford Academic. More on this topic Laparoscopic control of Danazol therapy on pelvic endometriosis.

Relationship between stage, site and morphological characteristics of pelvic endometriosis and pain. Laparoscopic treatment of deep endometriosis located on the uterosacral ligaments.

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