Corneal Collagen Cross-Linking with Riboflavin (also abbreviated as C3R) is a non-invasive corneal treatment shown to slow the progression of keratoconus. What is the treatment for Keratoconus? 1. Use of Contact Lenses (Corneal Collagen Crossling Procedure) . (Information & Appointments for C3R). Fax: Strengthens the cornea with less evasive procedures– The solution will I have done a c3r procedure in my left eye and after c3r my number is.

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Shroff Eye prcedure stood for excellence in eye care since A firm commitment to quality is at the heart of all services provided at our centers at Bandra W and Marine Drive, Mumbai. With current methods using rigid contact lens or intra corneal ring segments, only the refractive error spectacle numbers can be corrected, but it has very little effect on the progression of keratoconus.

A new non surgical, non invasive treatment, based on collagen cross linking with Ultraviolet A UVA, nm and riboflavin Vitamin B 2a photosensitizing agent is now available. This increase in corneal strength has shown to arrest procedute progression of keratoconus in numerous studies all over the world.

The treatment is performed in our operation theatre under complete sterile conditions. Usually, only one eye is treated in one sitting. The treatment is performed under topical anesthesia using anesthetic eye drops.

The surface of the eye cornea is treated with application of Riboflavin proccedure drops for 30 minutes.

Benefits of Corneal Collagen Crosslinking with Riboflavin

The eye is then exposed to UVA light for 30 minutes. Hence, the treatment takes about an hour per eye. After the treatment, antibiotic eye drops are applied; a bandage contact lens may be applied, which will be removed by our doctor during the follow up visit. Protective eye wear, such as sunglasses also given by us is to be worn for a few days until complete healing takes place. Collagen cross-linking treatment is c3 a cure for keratoconus, rather, it aims to slow or even halt the progression of the condition.


This is important to understand. The main aim of this treatment is to arrest progression of keratoconus, and thereby prevent further deterioration in vision and the need for corneal transplantation. Very few potential risks associated with this treatment have been reported so far.

The Ultraviolet light dose used is designed to prevent proceure to the cells that line the procesure of the cornea or the other structures within the eye. No lens opacities cataracts have been attributed to this treatment in European trials.

Until recently, there was no method to change the integrity and strength of the cornea itself for keratoconus patients. In published European studies, such treatments are proven safe and effective in patients.

The 3 and 5 year results of Dresden clinical study in human eyes has shown arrest of progression of keratoconus in all treated eyes. Crosslinking treatment of progressive keratoconus: Current Opinion in Ophthalmology ; Best corrected vision improved by 1.

Corneal Collagen Cross-Linking

This technique has shown great promise in treating early cases prodedure the disease. Initial management is tried with rigid contact lenses by our contact lens specialist. In very early stages of keratoconus, spectacles can suffice to correct minor astigmatism.

As the condition progresses, spectacles may no longer provide the patient with a satisfactory degree of visual acuity, and most doctors will move to managing the condition with contact lenses. Rigid gas permeable contact lenses for keratoconus improve vision by procedhre of tear fluid filling the gap between the irregular corneal surface and the smooth regular inner surface of the contact lens, thereby creating the effect of a smoother cornea.

The irregular cone needs expertise to produce a contact lens with optimal contact, stability and steepness. Some trial-and-error fitting might be necessary.


A soft contact lens has a tendency to conform to the conical shape of the cornea, thus diminishing its effect. These do not however prove effective for every patient. Precaution with contact lenses: There is a small risk of infection when wearing contact lenses and the risk becomes much greater if the contact lenses are not kept clean, so it is important to strictly follow the hygiene instructions given when the contact lenses are fitted.

The average amount of topographic improvement we have observed is about 2 D. A new world of natural vision could be waiting for you. What is Collagen Cross-linking? How is the treatment done? Who can benefit from this treatment? What are the risks and consequences involved? The treatment involves the outer layer epithelium profedure the cornea: There is therefore discomfort and a short-term haze.

Other lesser but more common risks include: Inability to wear contact lenses for several weeks after the treatment Changes in corneal shape necessitates fitting of a contact lens procedue a occasional change in spectacle correction. As is the case with any treatment, there may also be long-term risks that have not yet been identified. The increased corneal rigidity induced may wear off over time and further periodic treatments may be required.

How does Cross Linking arrest keratoconus? Are there any published studies for the same?

Learn more about Crosslinking of cornea using Accelerated C3R. Learn more about Topography link C3R. Talk to us today. Laser Vision Correction Surgery.

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